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With the development of immune disorders (myocarditis, nephritis, vasculitis), it is necessary to buy allopurinol online. Direct anticoagulants are used in all cases except fungal endocarditis. When circulatory failure develops, its treatment is carried out according to accepted regimens, including peripheral vasodilators, diuretics, angiotensin-converting enzyme inhibitors. For rhythm disturbances, antiarrhythmic drugs are prescribed.
Primary prevention involves the sanitation of foci of chronic infections, general strengthening and health measures. Special preventive measures are carried out in patients with an increased risk of developing infective endocarditis. This includes patients. Persons at risk require special medication preparation when carrying out the following manipulations. For prophylaxis, regimens using penicillins, cephalosporins, and macrolides are used. Infectious (bacterial) endocarditis. Video presentation.
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Classification of infective endocarditis Symptoms of zyloprim endocarditis Complications of infective endocarditis Diagnosis of infective endocarditis Treatment of infective endocarditis Prognosis for infective endocarditis Prevention of infective endocarditis Treatment prices. Infective endocarditis occurs when the following conditions are present. transient bacteremia, damage to the endocardium and vascular endothelium, changes in hemostasis and hemodynamics, immunity disorders. Bacteremia can develop due to existing foci of chronic infection or invasive medical procedures.
The leading role in the development of subacute infective endocarditis belongs to viridans streptococcus, in acute cases (for example, after open heart surgery) - Staphylococcus aureus, less often enterococcus, pneumococcus, and Escherichia coli. In recent years, the composition of infectious agents of endocarditis has changed. the number of primary acute endocarditis of staphylococcal nature has increased. With Staphylococcus aureus bacteremia, infective endocarditis develops in almost 100% of cases.
Endocarditis caused by gram-negative and anaerobic microorganisms and fungal infection has a severe course and is difficult to respond to antibiotic therapy. Fungal endocarditis occurs more often with long-term treatment with antibiotics in the postoperative period, with long-standing venous catheters.
Adhesion (sticking) of microorganisms to the endocardium is promoted by certain general and local factors. Common factors include severe immune disorders observed in patients undergoing immunosuppressive treatment, in alcoholics, drug addicts, and the elderly. Local include congenital and acquired anatomical damage to the heart valves, intracardiac hemodynamic disorders that occur with heart defects.
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Most subacute infective endocarditis develops with congenital heart defects or rheumatic lesions of the heart valves. Hemodynamic disturbances caused by heart defects contribute to microtrauma of the valves (mainly mitral and aortic) and changes in the endocardium. On the heart valves, characteristic ulcerative-warty changes develop that look like cauliflower (polypous deposits of thrombotic masses on the surface of the ulcers). Microbial colonies contribute to the rapid destruction of valves, which can occurtheir sclerosis, deformation and rupture. A damaged valve cannot function normally - heart failure develops, which progresses very quickly.
There is immune damage to the endothelium of small vessels of the skin and mucous membranes, leading to buy zyloprim online of vasculitis (thrombovasculitis, hemorrhagic capillary toxicosis). Characterized by impaired permeability of the walls of blood vessels and the appearance of small hemorrhages. Lesions of larger arteries are often observed. coronary and renal. Often an infection develops on a prosthetic valve, in which case the causative agent is most often streptococcus.
- The development of infective endocarditis is facilitated by factors that weaken the body’s immunological reactivity.
- The incidence of infective endocarditis is constantly increasing throughout the world.
- The risk group includes people with atherosclerotic, traumatic and rheumatic damage to the heart valves.
- Patients with ventricular septal defect and coarctation of the aorta have a high risk of infective endocarditis.
- Currently, the number of patients with prosthetic valves (mechanical or biological) and artificial pacemakers (pacemakers) has increased.
- The number of cases of infective endocarditis is increasing due to the use allopurinol pills and frequent intravenous infusions. Drug addicts often suffer from infective endocarditis.